GABA

The complexity of the neuronal connections is formed during development under the guidance of both genetic and environmental factors. The interplay between genetic blueprint and neuronal activity results in formation of synaptic connections pattern, unique for each individual. Genetic or environmental alterations in this process may push developing network towards pathological attractor state, leading to progression of a neurodevelopmental disorder.

Our research strategy is based on an integrative approach, where physiological and pathophysiological mechanisms are investigated from the molecular and cellular level to the whole organism. We also aim to bring a strong evolutionary perspective in the study of CNS disorders.